BDBM646588 6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimidin-2- yl]-1H-indole-3-sulfonamide::US20240025883, Example 93

SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Br)ccc23)nc(OC)c1CCC#N

InChI Key InChIKey=OVEMEJZFGNRPRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646588   

TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM646588(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)
Affinity DataIC50:  10nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent