BDBM646616 6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy-pyrimidin-2-yl]- 1H-pyrrolo[2,3-b]pyridine-3- sulfonamide::US20240025883, Example 121

SMILES COc1nc(NS(=O)(=O)c2c[nH]c3nc(Cl)ccc23)nc(OC)c1CCC(F)F

InChI Key InChIKey=LQZFFQVQDURTQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646616   

TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM646616(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)
Affinity DataIC50:  16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent