BDBM646729 6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyrimidin-2-yl]-7- (methylthio)-1H-indole-3- sulfonamide::US20240025883, Example 234
SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(SC)c(Cl)ccc23)ncc1CC(F)F
InChI Key InChIKey=SGGYGRHAJQDHHH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 646729
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 16nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair