BDBM646747 N-[5-(2-cyanoethyl)-4,6- dimethoxy-pyrimidin-2-yl]-6- (difluoromethyl)-7-fluoro-1H- indole-3-sulfonamide::US20240025883, Example 252::US20240025883, Example 253
SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(F)c(ccc23)C(F)F)nc(OC)c1CCC#N
InChI Key InChIKey=RSYUGWUOHOLUST-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 646747
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 20nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair