BDBM649440 US20240034743, Compound 129

SMILES CNC(=O)c1c(Nc2nc(Nc3cc4-c5cnn(C)c5CCN(C(C)C)c4cc3OC)ncc2Br)ccc2nccnc12

InChI Key InChIKey=XLKRIMOPSFMAKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649440   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Homo sapiens (Human))
Qilu Pharmaceutical Co.

US Patent
LigandPNGBDBM649440(US20240034743, Compound 129)
Affinity DataIC50: <1nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Qilu Pharmaceutical Co.

US Patent
LigandPNGBDBM649440(US20240034743, Compound 129)
Affinity DataIC50:  5.5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent