BDBM76395 (E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one::(E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one::MLS000438984::SMR000113000::cid_5331295

SMILES COc1ccc(\C=C\C(=O)c2ccccc2O)cc1

InChI Key InChIKey=NXBNYUSXDBHELA-DHZHZOJOSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 76395   

TargetShiga toxin subunit A(Shigella dysenteriae)
TBA

Curated by ChEMBL
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataKi:  9.93E+3nMAssay Description:Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit assessed as change in transition temperature by SYPRO orange dye based fluorescence-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 6(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50:  6.00E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-diphosphohydrolase 1(Schistosoma mansoni)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50:  3.06E+4nMAssay Description:Inhibition of Schistosoma mansoni ATPDase1 incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Quaid-I-Azam University

LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50:  9.29E+4nMpH: 8.0 T: 2°CAssay Description:In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 8(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50:  1.06E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCaspase-3(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50:  2.31E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay