BDBM7737 4-[2-(4-Chloro-5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]benzenesulfonamide::4-{2-[(3Z)-4-chloro-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzene-1-sulfonamide::Oxindole-Based Inhibitor 73

SMILES Cc1ccc2NC(=O)C(=NNc3ccc(cc3)S(N)(=O)=O)c2c1Cl

InChI Key InChIKey=BNAYALSWOQOGRV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 7737   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7737(4-[2-(4-Chloro-5-methyl-2-oxo-1,2-dihydro-3H-indol...)
Affinity DataIC50:  250nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7737(4-[2-(4-Chloro-5-methyl-2-oxo-1,2-dihydro-3H-indol...)
Affinity DataIC50:  13nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7737(4-[2-(4-Chloro-5-methyl-2-oxo-1,2-dihydro-3H-indol...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7737(4-[2-(4-Chloro-5-methyl-2-oxo-1,2-dihydro-3H-indol...)
Affinity DataIC50:  13nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7737(4-[2-(4-Chloro-5-methyl-2-oxo-1,2-dihydro-3H-indol...)
Affinity DataIC50:  250nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed