BDBM81441 CDK Inhibitor, 14

SMILES Cc1c(sc(=O)n1C)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1

InChI Key InChIKey=CGGMDMYBCWDOLZ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 81441   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Cyclacel

LigandPNGBDBM81441(CDK Inhibitor, 14)
Affinity DataKi:  0.380nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM81441(CDK Inhibitor, 14)
Affinity DataKi:  0.400nMAssay Description:Inhibition of recombinant human His-tagged CDK9/cyclin T1 expressed in baculovirus infected sf9 cells using (biotinyl-Ahx-(Tyr-Ser-ProThr-Ser-Pro-Ser...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Cyclacel

LigandPNGBDBM81441(CDK Inhibitor, 14)
Affinity DataKi:  2.30nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Cyclacel

LigandPNGBDBM81441(CDK Inhibitor, 14)
Affinity DataKi:  2.30nMAssay Description:Inhibition of CDK7 (unknown origin) using (biotinyl-Ahx-(Tyr-Ser-ProThr-Ser-Pro-Ser)4-NH2 as substrate after 45 mins by [gamma-32P]ATP based microbet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Cyclacel

LigandPNGBDBM81441(CDK Inhibitor, 14)
Affinity DataKi:  68nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM81441(CDK Inhibitor, 14)
Affinity DataKi:  149nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM81441(CDK Inhibitor, 14)
Affinity DataKi:  149nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Cyclacel

LigandPNGBDBM81441(CDK Inhibitor, 14)
Affinity DataKi:  449nMAssay Description:Kinase assay using cyclin-dependant kinases (CDK).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed