BDBM82354 1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1 H-indole, 4c

SMILES C(CN1CCN(CC1)c1ccccc1)Cn1ccc2ccccc12

InChI Key InChIKey=VXILQLXJSINXHA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 82354   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM82354(1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation count...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM82354(1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1...)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]N-methylspiperone from human D3R receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM82354(1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1...)
Affinity DataKi:  724nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

LigandPNGBDBM82354(1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1...)
Affinity DataKi:  1.49E+3nM ΔG°:  -8.26kcal/molepH: 7.4 T: 2°CAssay Description:The test was performed with the radioligand [3H]-(+)-pentazocine (42.5 Ci/mmol) from Perkin Elmer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed