BDBM8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1
SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO
InChI Key InChIKey=BSIZUMJRKYHEBR-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 8465
Affinity DataKi: 43nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of truncated stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibition of matrix metalloprotease 3More data for this Ligand-Target Pair
Affinity DataIC50: 19nMT: 2°CAssay Description:Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of MMP3 using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3.More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataKd: 43nMAssay Description:Binding affinity to stromelysin-1 catalytic domainMore data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Binding affinity to stromelysin-1 catalytic domain expressed in Escherichia coli BL21 (DE3) by isothermal titration colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MMP3 (Tyr18 to Cys477 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair