BDBM86012 Chalcone, 11

SMILES Oc1ccc(Cl)cc1C(=O)\C=C\c1ccc(Cl)cc1

InChI Key InChIKey=TTWITESQDJUURJ-XVNBXDOJSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86012   

TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM86012(Chalcone, 11)
Affinity DataKi:  7.17E+4nM ΔG°:  -5.65kcal/molepH: 8.0 T: 2°CAssay Description:In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha chain(Ovis aries)TBA
LigandPNGBDBM86012(Chalcone, 11)
Affinity DataIC50:  2.03E+4nMAssay Description:Inhibition of Ovis aries (sheep) brain tubulin polymerization assessed as microtubule assembly after 15 min by measuring turbidity based spectroscopi...More data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)TBA
LigandPNGBDBM86012(Chalcone, 11)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article