BDBM86776 Phthalonitrile analogue, 4e
SMILES N#Cc1ccc(OC\C=C\c2ccccc2)cc1C#N
InChI Key InChIKey=HWZWTQAGSPYDRR-QPJJXVBHSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 86776
Affinity DataIC50: 399nMpH: 7.4 T: 2°CAssay Description:MAO inhibition potencies of phthalonitrile, benzonitrile and benzyl phenyl ether analogs, recombinant human MAO-A and -B were employed as enzyme sour...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Yaroslavl State Technical University
Curated by ChEMBL
Yaroslavl State Technical University
Curated by ChEMBL
Affinity DataIC50: 642nMAssay Description:Inhibition of human recombinant MAO-B assessed as kynuramine oxidation to 4-hydroxyquinoline formation by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 399nMAssay Description:Inhibition of human recombinant MAO-A assessed as kynuramine oxidation to 4-hydroxyquinoline formation by spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Yaroslavl State Technical University
Curated by ChEMBL
Yaroslavl State Technical University
Curated by ChEMBL
Affinity DataIC50: 6.60nMpH: 7.4 T: 2°CAssay Description:MAO inhibition potencies of phthalonitrile, benzonitrile and benzyl phenyl ether analogs, recombinant human MAO-A and -B were employed as enzyme sour...More data for this Ligand-Target Pair