BDBM88008 US10245267, Example 1043::US10709712, Example 1043::US9694016, 1043
SMILES Cc1ncc(NC(=O)c2ccnc(c2)S(C)(=O)=O)cc1-c1cc(NCCO)nc(c1)N1CCOCC1
InChI Key InChIKey=KRAKJGFWCBETHP-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 88008
Affinity DataIC50: 3.71nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 22.8nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair