BDBM91684 Pyrazolyl benzenesulfonamide derivative, 9a

SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(C#N)c(n1)-c1ccccc1

InChI Key InChIKey=YYHQERMVVNSDSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 91684   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50:  780nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1 [582-599](Homo sapiens (Human))
University of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50: >1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed