BDBM92626 Pyrido analog, 3

SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O

InChI Key InChIKey=IMLLFFIWQIAPHC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92626   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM92626(Pyrido analog, 3)
Affinity DataIC50:  2nMAssay Description:Inhibition of SYK (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 25 m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM92626(Pyrido analog, 3)
Affinity DataIC50:  2.10nMpH: 7.4 T: 2°CAssay Description:A Lance TR-FRET assay (Perkin Elmer) was used to measure and compare the potency of compounds against Syk kinase domain.More data for this Ligand-Target Pair