BDBM97500 Roche-Dataset for PDE10A, Compound 91::US8470820, 11

SMILES COCc1ccc(Nc2cncnc2)c(n1)C(=O)Nc1cc(nn1CCO)-c1ccccn1

InChI Key InChIKey=GOTMAOILGUWVLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97500   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM97500(Roche-Dataset for PDE10A, Compound 91 | US8470820,...)
Affinity DataIC50:  5.24nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM97500(Roche-Dataset for PDE10A, Compound 91 | US8470820,...)
Affinity DataIC50:  5nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails US Patent