BDBM97500 Roche-Dataset for PDE10A, Compound 91::US8470820, 11
SMILES COCc1ccc(Nc2cncnc2)c(n1)C(=O)Nc1cc(nn1CCO)-c1ccccn1
InChI Key InChIKey=GOTMAOILGUWVLE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 97500
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 5.24nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 5nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair