BDBM97522 Roche-Dataset for PDE10A, Compound 56::US8470820, 33
SMILES O=C(Nc1cc(nn1CCC#N)-c1ccccn1)c1nc(ccc1Nc1cncnc1)C1CC1
InChI Key InChIKey=WCIXFYJKRPWISF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 97522
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 170nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 170nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair