BDBM97531 Roche-Dataset for PDE10A, Compound 35::US8470820, 42

SMILES CN(C)CCn1nc(NC(=O)c2nc(ccc2Nc2cncnc2)C2CC2)cc1-c1ccccn1

InChI Key InChIKey=YTMOUNMEHGJTCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97531   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM97531(Roche-Dataset for PDE10A, Compound 35 | US8470820,...)
Affinity DataIC50:  24nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM97531(Roche-Dataset for PDE10A, Compound 35 | US8470820,...)
Affinity DataIC50:  24nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair
In DepthDetails US Patent