BDBM98029 US10472367, Compound Formula III::US10919901, Compound Formula III::US8487096, III::US9221824, Formula III

SMILES C[C@H](NC(=O)c1ccc(cc1Cl)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1)c1noc(C)n1

InChI Key InChIKey=DWJDZWDADHMBCL-HNNXBMFYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98029   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM98029(US10472367, Compound Formula III | US10919901, Com...)
Affinity DataIC50:  0.550nMpH: 7.5 T: 2°CAssay Description:The compounds of the intervention were screened in vitro for their ability to inhibit c-Met kinase activity. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM98029(US10472367, Compound Formula III | US10919901, Com...)
Affinity DataIC50:  0.550nMAssay Description:The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-Met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM98029(US10472367, Compound Formula III | US10919901, Com...)
Affinity DataIC50:  0.550nMAssay Description:The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. Briefly, histidine-tagged c-Met catalytic d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM98029(US10472367, Compound Formula III | US10919901, Com...)
Affinity DataIC50:  0.550nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent