BDBM98578 3-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]sulfamoylmethyl]benzoic acid::US8476306, 6.3

SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2cccc(c2)C(O)=O)cc1

InChI Key InChIKey=FVQTZAVABYIQGN-QGZVFWFLSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98578   

TargetUrokinase plasminogen activator surface receptor(Rat)
The Medicines

US Patent
LigandPNGBDBM98578(3-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  160nM ΔG°:  -9.23kcal/moleT: 24°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSerine protease 1(Rat)
The Medicines

US Patent
LigandPNGBDBM98578(3-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  720nM ΔG°:  -8.35kcal/moleT: 24°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In DepthDetails US Patent

TargetPlasminogen(Rat)
The Medicines

US Patent
LigandPNGBDBM98578(3-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  5.90E+4nM ΔG°:  -5.75kcal/moleT: 24°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProthrombin(Rat)
The Medicines

US Patent
LigandPNGBDBM98578(3-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...)
Affinity DataKi:  1.50E+5nM ΔG°:  -5.20kcal/moleT: 24°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent