BDBM98596 (2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]-2-[(4-fluorophenyl)methylsulfonylamino]-3-hydroxy-propanamide::US8476306, 6.22

SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(F)cc2)cc1

InChI Key InChIKey=PLWLISMFLWIBNF-QGZVFWFLSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98596   

TargetUrokinase plasminogen activator surface receptor(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98596((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  31nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98596((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  110nM ΔG°:  -9.45kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98596((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  7.90E+3nM ΔG°:  -6.93kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98596((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  2.00E+4nM ΔG°:  -6.38kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In DepthDetails US Patent