BDBM98603 3-amino-N-[4-[[(2S)-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]phenyl]-4-methoxy-benzamide::US8476306, 12

SMILES NC(=N)c1ccc(CNC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CO)NS(=O)(=O)Cc2ccccc2)cc1

InChI Key InChIKey=LEHTWFAAQZWNNG-SFTDATJTSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98603   

TargetSerine protease 1(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98603(3-amino-N-[4-[[(2S)-2-[[(2R)-2-(benzylsulfonylamin...)
Affinity DataKi:  25nM ΔG°:  -10.3kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUrokinase plasminogen activator surface receptor(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98603(3-amino-N-[4-[[(2S)-2-[[(2R)-2-(benzylsulfonylamin...)
Affinity DataKi:  110nM ΔG°:  -9.45kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasminogen(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98603(3-amino-N-[4-[[(2S)-2-[[(2R)-2-(benzylsulfonylamin...)
Affinity DataKi:  400nM ΔG°:  -8.69kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98603(3-amino-N-[4-[[(2S)-2-[[(2R)-2-(benzylsulfonylamin...)
Affinity DataKi:  8.50E+3nM ΔG°:  -6.89kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent