BDBM98679 US8497286, 155

SMILES CCOC[C@@H](CC(C)C)NC(=O)[C@@H]1CNC[C@@H](C1)C(=O)N(C1CC1)c1cc(OC)c(cn1)C(C)C

InChI Key InChIKey=AOJMWYPUZRQUTK-PWRODBHTSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98679   

TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98679(US8497286, 155)
Affinity DataIC50:  0.900nMAssay Description:Inhibition activity of renin using FRET assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98679(US8497286, 155)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant renin in presence of human plasma using Ac- IHPFHL-VIHNK-(DY-505-X5)-COOH substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM98679(US8497286, 155)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant renin using fluorescence-quenched RE(EDANS)IHPFHLVIHTK(Dabcyl)R substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM98679(US8497286, 155)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cell membranes incubated for 90 mins by beta-counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed