Affinity DataIC50: 0.251nMAssay Description:Binding affinity to full-length BRD4 short isoform (unknown origin) by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human BRD4 bromodomain 1 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human BRD4 bromodomain 1/2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Inhibition of human BRD3 bromodomain 1 by BROMOscan assayMore data for this Ligand-Target Pair
TargetBromodomain and PHD finger-containing protein 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of human BRPF3 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.30nMAssay Description:Inhibition of human BRD7 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human BRD3 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human BRD4 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human BRD2 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: <4nMAssay Description:Inhibition of human BRPF1 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.020-0.026)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.020-0.026)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.019-0.032)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.029-0.032)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.021-0.042)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.038-0.042)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.040-0.044)More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of BRDT (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 194nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 199nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Binding affinity to BRD3 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Binding affinity to BRD3 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysisMore data for this Ligand-Target Pair