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Found 154 with Last Name = 'capraro' and Initial = 'hg'
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046206(2,2'-bipyridine-6,6'-dicarboximidamide | CHEMBL151...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046197(4-{3-[(Z)-amino(imino)methyl]phenyl}pyrimidine-2-c...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50:  8.5nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066461(CHEMBL326408 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  13nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066474(((S)-1-{(1S,2S)-1-Benzyl-2-hydroxy-3-[N'-((S)-2-me...)
Affinity DataIC50:  14nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066462(CHEMBL326347 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  16nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066473(CHEMBL325900 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  18nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066476(CHEMBL333386 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  20nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066459(((S)-1-{(1S,2S)-1-Benzyl-3-[N'-((S)-2-ethoxycarbon...)
Affinity DataIC50:  22nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM213(2-Methyl-4-[[N-(methoxycarbonyl)-L-valinyl]amino]-...)
Affinity DataIC50:  23nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073765(CHEMBL367625 | N*2*-((1R,2S)-2-Amino-cyclohexyl)-N...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)
Affinity DataIC50:  26nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066475(((S)-1-{N'-[(2S,3S)-2-Hydroxy-3-((S)-2-methoxycarb...)
Affinity DataIC50:  27nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM206(1-Cyclohexyl-2-N-[[(methoxycarbonyl)-L-valinyl]ami...)
Affinity DataIC50:  27nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073795(4-[9-Ethyl-6-(3-trifluoromethyl-phenylamino)-9H-pu...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066472(((S)-1-{(1S,2S)-1-Benzyl-2-hydroxy-3-[N'-((S)-2-me...)
Affinity DataIC50:  28nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073763(3-[9-Ethyl-2-(4-hydroxy-cyclohexylamino)-9H-purin-...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066468(CHEMBL324521 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  29nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073755(4-[6-(3-Chloro-phenylamino)-9-ethyl-9H-purin-2-yla...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Cyclin-dependent kinase 1, CDK1-related human bladder carcinoma (T24) cell protliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073796(4-[6-(3-Chloro-phenylamino)-9-ethyl-9H-purin-2-yla...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073765(CHEMBL367625 | N*2*-((1R,2S)-2-Amino-cyclohexyl)-N...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066463(((S)-1-{(1S,2S)-1-Benzyl-2-hydroxy-3-[N'-((S)-2-me...)
Affinity DataIC50:  31nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM214(1-(4-Methoxyphenyl)-2-[[N-(methoxycarbonyl)-L-vali...)
Affinity DataIC50:  31nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073764(CHEMBL171891 | N*2*-(4-Amino-cyclohexyl)-9-ethyl-N...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073765(CHEMBL367625 | N*2*-((1R,2S)-2-Amino-cyclohexyl)-N...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066465(CHEMBL442013 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  32nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073767(4-[9-Ethyl-6-(3-fluoro-phenylamino)-9H-purin-2-yla...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066467(CHEMBL114039 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  33nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066469(CHEMBL113943 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  34nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066471(((S)-1-{N'-Biphenyl-4-ylmethyl-N'-[(2S,3S)-2-hydro...)
Affinity DataIC50:  35nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046189((2E)-2-{3-[(Z)-amino(imino)methyl]benzylidene}hydr...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM216(2-Methyl-4-[[N-(benzyloxycarbonyl)-L-valinyl]amino...)
Affinity DataIC50:  37nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073766(CHEMBL176559 | {1-[6-(3-Chloro-phenylamino)-9-ethy...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073759(CHEMBL173459 | N*2*-(4-Amino-cyclohexyl)-N*6*-(3-c...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073794(CHEMBL367691 | N*2*-(4-Amino-cyclohexyl)-N*6*-(3-c...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073759(CHEMBL173459 | N*2*-(4-Amino-cyclohexyl)-N*6*-(3-c...)
Affinity DataIC50:  39nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073798(4-[9-Ethyl-6-(4-fluoro-phenylamino)-9H-purin-2-yla...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073777(CHEMBL368351 | [2-((R)-2-Aminomethyl-pyrrolidin-1-...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against cyclin-dependent kinase 1 (CDK1) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM215(1-Cyclohexyl-2-[[N-(benzyloxycarbonyl)-L-valinyl]a...)
Affinity DataIC50:  41nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066464(CHEMBL116165 | {(S)-1-[N'-[(2S,3S)-2-Hydroxy-3-((S...)
Affinity DataIC50:  41nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066477(((S)-1-{N'-(4-Diethylamino-benzyl)-N'-[(2S,3S)-2-h...)
Affinity DataIC50:  41nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM217(1-(4-Methoxyphenyl)-2-[[N-(benzyloxycarbonyl)-L-va...)
Affinity DataIC50:  49nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066460(((S)-1-{N'-Biphenyl-4-ylmethyl-N'-[(2S,3S)-2-hydro...)
Affinity DataIC50:  51nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM207(1-Cyclohexyl-2-[[N-(ethoxycarbonyl)-L-valinyl]amin...)
Affinity DataIC50:  56nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50066466(((S)-1-{N'-Biphenyl-4-ylmethyl-N'-[(2S,3S)-2-hydro...)
Affinity DataIC50:  58nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046196(3-((E)-{[(Z)-((2E)-2-{3-[(E)-amino(imino)methyl]be...)
Affinity DataIC50:  61nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM211(2-methoxyethyl N-[(1S)-1-{[(2S,3S)-4-[(2S)-N'-(cyc...)
Affinity DataIC50:  62nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50046200((2E)-2-(1-{3-[(E)-amino(imino)methyl]phenyl}ethyli...)
Affinity DataIC50:  66nMAssay Description:Inhibitory concentration of compound against S-Adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM208(CGP 53820 analog | methyl N-[(1S)-1-{[(2S,3S)-4-[(...)
Affinity DataIC50:  67nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Ciba-Geigy

LigandPNGBDBM205(2-(2-methoxyethoxy)ethyl N-[(1S)-1-{[(2S,3S)-4-[(2...)
Affinity DataIC50:  67nMpH: 6.0 T: 2°CAssay Description:A peptide cleavage assay was performed using the icosapeptide H-Arg-Arg-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Asn-Ile-Gln-Gly-Arg-Arg-OH, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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