Found 749 with Last Name = 'smith' and Initial = 'jl' Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 0.309nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 0.312nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human wild type partial length PIKfyve (F1512 to C2098 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 2.85nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill
Curated by ChEMBL
University Of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
