Affinity DataKi: 0.600nMAssay Description:Binding affinity to human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with wild type Cannabinoid receptor 1More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 7.42nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with F3.25 (190)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with wild type Cannabinoid receptor 1More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with F3.36 (201)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with F3.25 (190)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with W6 48(357)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 34.4nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 39.2nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with W6 48(357)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 53.4nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -41.2kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with F3.36 (201)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 170nM ΔG°: -38.6kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 185nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 199nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with W5 43(280)A mutant Cannabinoid receptor 1 at 5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 233nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with W6 48(357)A mutant in Cannabinoid receptor 1More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with W5 43(280)A mutant Cannabinoid receptor 1 at 5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with wild type Cannabinoid receptor 1More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with F3.36 (201)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 320nM ΔG°: -37.1kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 389nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
Affinity DataKi: 527nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.22E+3nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: >1.50E+3nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Forbes Norris Als/Mda Research Center
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with F3.25 (190)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nM ΔG°: -32.7kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nM ΔG°: -30.8kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nM ΔG°: -27.1kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Ability to displace [125I]- labeled MIP-1alpha from CCR5 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Ability to displace [125I]- labeled MIP-1alpha from CCR5 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Ability to displace [125I]- labeled MIP-1alpha from CCR5 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Ability to displace [125I]-labeled MIP-1alpha from the C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranesMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranesMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of [33P]-S1P binding to human Sphingosine 1-phosphate receptor 1 expressed on CHO cell membranesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Ability to displace [125I]- labeled MIP-1alpha from CCR5 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Ability to displace [125I]- labeled MIP-1alpha from CCR5 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair