Compile Data Set for Download or QSAR
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Found 172 with Last Name = 'schubenel' and Initial = 'r'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50402073(CHEMBL2206008)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477339(BMS-299897 | CHEMBL247471)
Affinity DataIC50:  7.10nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50402072(CHEMBL2206013)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50402070(CHEMBL2206017)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50402071(CHEMBL2206015)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484116(CHEMBL1812401)
Affinity DataIC50: >500nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta38 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50263829(3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...)
Affinity DataIC50:  2.57E+3nMAssay Description:Inhibition of human CK1delta expressed in simian genome expressing mouse 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  2.90E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  2.90E+3nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  5.80E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477330(CHEMBL218756)
Affinity DataIC50:  5.80E+3nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta38 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484099(CHEMBL375635)
Affinity DataIC50: >6.90E+3nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477329(CHEMBL392028)
Affinity DataIC50:  7.50E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477329(CHEMBL392028)
Affinity DataIC50:  7.80E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477327(CHEMBL385554)
Affinity DataIC50:  8.50E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481894(CHEMBL1079649)
Affinity DataIC50:  9.00E+3nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477327(CHEMBL385554)
Affinity DataIC50:  9.30E+3nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477335(CHEMBL247693)
Affinity DataIC50:  1.10E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484109(CHEMBL1812426)
Affinity DataIC50:  1.29E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477338(CHEMBL248090)
Affinity DataIC50:  1.30E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477331(CHEMBL396693)
Affinity DataIC50:  1.30E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477325(CHEMBL248089)
Affinity DataIC50:  1.30E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481901(CHEMBL1079633)
Affinity DataIC50:  1.30E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481903(CHEMBL1081052)
Affinity DataIC50:  1.31E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477324(CHEMBL392639)
Affinity DataIC50:  1.60E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481893(CHEMBL1080015)
Affinity DataIC50:  1.70E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477328(CHEMBL247692)
Affinity DataIC50:  1.70E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477337(CHEMBL247691)
Affinity DataIC50: >1.90E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477329(CHEMBL392028)
Affinity DataIC50:  1.90E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-40 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477337(CHEMBL247691)
Affinity DataIC50:  1.90E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477327(CHEMBL385554)
Affinity DataIC50: >2.00E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-40 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481902(CHEMBL1081051)
Affinity DataIC50:  2.24E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481890(CHEMBL1075792)
Affinity DataIC50:  2.37E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484105(CHEMBL1812408)
Affinity DataIC50:  2.40E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477338(CHEMBL248090)
Affinity DataIC50:  2.40E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477337(CHEMBL247691)
Affinity DataIC50:  2.40E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481905(CHEMBL1079451)
Affinity DataIC50:  2.60E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484118(CHEMBL1812423)
Affinity DataIC50:  2.70E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484104(CHEMBL1812407)
Affinity DataIC50:  2.80E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477328(CHEMBL247692)
Affinity DataIC50:  3.00E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484105(CHEMBL1812408)
Affinity DataIC50:  3.10E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta38 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484130(CHEMBL1812428)
Affinity DataIC50:  3.10E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477332(CHEMBL247491)
Affinity DataIC50:  3.20E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50477332(CHEMBL247491)
Affinity DataIC50:  3.20E+4nMAssay Description:Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484105(CHEMBL1812408)
Affinity DataIC50:  3.20E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta40 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484129(CHEMBL1812416)
Affinity DataIC50:  3.20E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481892(CHEMBL1075794)
Affinity DataIC50: >3.26E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50484116(CHEMBL1812401)
Affinity DataIC50: >3.50E+4nMAssay Description:Modulation of gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in amyloid beta42 production after 20 to 24 hrs by li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481899(CHEMBL1079820)
Affinity DataIC50:  3.61E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Darmstadt University of Technology

Curated by ChEMBL
LigandPNGBDBM50481897(CHEMBL1081582)
Affinity DataIC50:  3.62E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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