Compile Data Set for Download or QSAR
maximum 50k data
Found 221 with Last Name = 'madhavi' and Initial = 'yv'
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataKi:  0.00700nMAssay Description:Inhibition of wild type Escherichia coli FabI assessed as inhibition of bacterial growthMore data for this Ligand-Target Pair
LigandPNGBDBM36537(2-phenoxylphenol | PT51 | US10071965, Compound PT5...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of wild type Escherichia coli FabI assessed as inhibition of bacterial growthMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM36538(5-fluoro-2-phenoxylphenol | PT55 | US10071965, Com...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of wild type Escherichia coli FabI assessed as inhibition of bacterial growthMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM36539(5-chloro-2-phenoxylphenol | PT52 | US10071965, Com...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of wild type Escherichia coli FabI assessed as inhibition of bacterial growthMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataKi:  5nMAssay Description:Inhibition of Staphylococcus aureus FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
LigandPNGBDBM36542(5-methyl-2-phenoxylphenol | PT53 | US10071965, Com...)
Affinity DataKi:  7nMAssay Description:Inhibition of wild type Escherichia coli FabI assessed as inhibition of bacterial growthMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataKi:  200nMAssay Description:Inhibition of Mycobacterial tuberculosis ATCC 25618 FabI assessed as measuring NADH consumption rateMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50443008(Pyridomycin)
Affinity DataKi:  4.55E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhA S94AMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50443008(Pyridomycin)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis wild type InhAMore data for this Ligand-Target Pair
LigandPNGBDBM50408387(CHEMBL5268482)
Affinity DataIC50:  0.0400nMAssay Description:Antagonist activity at human P2X7 receptor transfected in THP1 cells assessed as inhibition of benzoyl-ATP-induced changes in plasma membrane pore fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50408386(CHEMBL5287343)
Affinity DataIC50:  0.260nMAssay Description:Antagonist activity at human P2X7 receptor transfected in THP1 cells assessed as inhibition of benzoyl-ATP-induced changes in plasma membrane pore fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50142954(4-[(E)-2-({1-[2,4-Dichloro-3-(4-imidazol-1-yl-2-me...)
Affinity DataIC50:  0.260nMAssay Description:Displacement of [3H]bradykinin from human recombinant bradykinin B2 receptor expressed in CHO cells incubated for 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50481806(CHEMBL5269135)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of Staphylococcus aureus FabI assessed as inhibition of bacterial growth by measuring the NADH consumption rate at 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50481809(CHEMBL5268904)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of Staphylococcus aureus FabI assessed as inhibition of bacterial growth by measuring the NADH consumption rate at 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50481808(CHEMBL5273284)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of Staphylococcus aureus FabI assessed as inhibition of bacterial growth by measuring the NADH consumption rate at 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50481807(CHEMBL5291446)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of Staphylococcus aureus FabI assessed as inhibition of bacterial growth by measuring the NADH consumption rate at 20 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetB2 bradykinin receptor(Cavia porcellus)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50067290(5-{2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxy...)
Affinity DataIC50:  0.460nMAssay Description:Displacement of [3H]BK from Bradykinin B2 Receptor in guinea pig ileum by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50411638(CHEMBL404371)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at human P2X7 receptor transfected in THP1 cells assessed as inhibition of benzoyl-ATP-induced changes in plasma membrane pore fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at human P2X7 receptor transfected in THP1 cells assessed as inhibition of benzoyl-ATP-induced changes in plasma membrane pore fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human P2X7 receptor transfected in THP1 cells assessed as inhibition of benzoyl-ATP-induced changes in plasma membrane pore fo...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515481(CHEMBL4439680)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of VEGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515483(CHEMBL4466350)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of VEGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))TBA
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity in phenoxybenzamine-treated rat by Pressor assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50443004(CHEMBL3088173)
Affinity DataIC50:  4nMAssay Description:Inhibition of Mycobacterium tuberculosis ATCC 25618 InhAMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity in rat uterus by uterotonic assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  4.5nMAssay Description:Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)TBA
LigandPNGBDBM50481812(CHEMBL5284077)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of Mycobacterial tuberculosis ATCC 25618 FabI assessed as measuring NADH consumption rateMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50259155((Z)-Hymenialdisine | Hymenialdisine)
Affinity DataIC50:  6nMAssay Description:Antagonist potency on BK-induced contraction of guinea pig ileum longitudinal smooth muscleMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))TBA
LigandPNGBDBM50256044(5-(2-amino-4-oxo-1H-imidazol-5(4H)-ylidene)-2,3,4,...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity in rat uterus by uterotonic assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515483(CHEMBL4466350)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515481(CHEMBL4439680)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  9nMAssay Description:Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))TBA
LigandPNGBDBM50259155((Z)-Hymenialdisine | Hymenialdisine)
Affinity DataIC50:  10nMAssay Description:Antagonist activity in phenoxybenzamine-treated rat by Pressor assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50399407(CHEMBL2178284 | MUT056399)
Affinity DataIC50:  12nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50399407(CHEMBL2178284 | MUT056399)
Affinity DataIC50:  12nMAssay Description:Inhibition of Staphylococcus aureus FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50408185(CHEMBL5265856)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at rat UT receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50408186(CHEMBL5272006)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at rat UT receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50052244(CHEMBL1652621)
Affinity DataIC50:  14nMAssay Description:Inhibition of Staphylococcus aureus FabI assessed as inhibition of bacterial growth by measuring the NADH consumption rate at 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))TBA
LigandPNGBDBM50256003(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity in phenoxybenzamine-treated rat by Pressor assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))TBA
LigandPNGBDBM50363648(CHEMBL1947252)
Affinity DataIC50:  14nMAssay Description:Antagonist activity in phenoxybenzamine-treated rat by Pressor assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  15nMAssay Description:Activity at human B2 receptor transfected in CHO cells assessed as ability to antagonize BK-induced inositol-phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity in rat uterus by uterotonic assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))TBA
LigandPNGBDBM50363646(CHEMBL1947250)
Affinity DataIC50:  20nMAssay Description:Antagonist activity in rat uterus by uterotonic assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  20nMAssay Description:Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  22nMAssay Description:Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))TBA
LigandPNGBDBM50166289(CHEBI:43645 | CHEMBL216543)
Affinity DataIC50:  22nMAssay Description:Antagonist activity in phenoxybenzamine-treated rat by Pressor assayMore data for this Ligand-Target Pair
LigandPNGBDBM50259155((Z)-Hymenialdisine | Hymenialdisine)
Affinity DataIC50:  22nMAssay Description:Antagonist effect against 2-methyl-5-HT activity at 5-HT3 receptor in longitudinal muscle myenteric plexus from guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))TBA
LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity in rat uterus by uterotonic assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human M3 receptor assessed as inhibition of carbachol bindingMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)
Affinity DataIC50:  24nMAssay Description:Activity at human B2 receptor transfected in CHO cells assessed as ability to antagonize BK-induced inositol-phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails PubMed
Displayed 1 to 50 (of 221 total ) | Next | Last >>
Jump to: