TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to GST-tagged EED (unknown origin) assessed as inhibition constant incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity to GST-tagged EED (unknown origin) assessed as inhibition constant incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Inhibitory activity against Flk1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 69nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 2.09E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 3.17E+3nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 4.27E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 6.11E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 8.77E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Harbin Institute Of Technology
Curated by ChEMBL
Harbin Institute Of Technology
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
National Hellenic Research Foundation
Curated by ChEMBL
National Hellenic Research Foundation
Curated by ChEMBL
Affinity DataKi: 9.00E+5nMpH: 6.8Assay Description:Competitive inhibition of rabbit muscle glycogen phosphorylase b assessed as inorganic phosphate release using alphaD glucose-1-phosphate as substrat...More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
National Hellenic Research Foundation
Curated by ChEMBL
National Hellenic Research Foundation
Curated by ChEMBL
Affinity DataKi: 1.30E+6nMpH: 6.8Assay Description:Competitive inhibition of rabbit muscle glycogen phosphorylase b assessed as inorganic phosphate release using alphaD glucose-1-phosphate as substrat...More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
National Hellenic Research Foundation
Curated by ChEMBL
National Hellenic Research Foundation
Curated by ChEMBL
Affinity DataKi: 1.70E+6nMpH: 6.8Assay Description:Competitive inhibition of rabbit muscle glycogen phosphorylase b assessed as inorganic phosphate release using alphaD glucose-1-phosphate as substrat...More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of His-tagged EED (unknown origin) incubated for 30 mins in presence of biotinylated H3K27me3 peptide (19 to 33 aa) by alpha screening com...More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of PRC2 complex of EZH2-EED-SUZ12 (unknown origin) using human nucleosome as substrate incubated for 70 mins in presence of [3H]SAMMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: <20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: <20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: <20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: <20nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Binding affinity to BRD4 bromodomain 1 in human Ramos cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair