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Found 228 with Last Name = 'abulwerdi' and Initial = 'f'
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511123(CHEMBL4522193)
Affinity DataKi:  73nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511124(CHEMBL4533559)
Affinity DataKi:  74nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511123(CHEMBL4522193)
Affinity DataKi:  84nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511125(CHEMBL4462138)
Affinity DataKi:  87nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511136(CHEMBL4558313)
Affinity DataKi:  90nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  94nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  100nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511124(CHEMBL4533559)
Affinity DataKi:  100nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238185(US9394303, 57)
Affinity DataKi:  130nM ΔG°:  -39.3kJ/mole IC50:  670nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511136(CHEMBL4558313)
Affinity DataKi:  150nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511125(CHEMBL4462138)
Affinity DataKi:  170nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013865(CHEMBL3265297)
Affinity DataKi:  170nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013867(CHEMBL3265299)
Affinity DataKi:  180nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511143(CHEMBL4463305)
Affinity DataKi:  200nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238190(US9394303, 16)
Affinity DataKi:  210nM ΔG°:  -38.1kJ/mole IC50:  1.11E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013891(CHEMBL3260032)
Affinity DataKi:  210nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511135(CHEMBL4457901)
Affinity DataKi:  220nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013866(CHEMBL3265298)
Affinity DataKi:  240nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238186(US9394303, 58)
Affinity DataKi:  250nM ΔG°:  -37.7kJ/mole IC50:  1.28E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511139(CHEMBL4454113)
Affinity DataKi:  250nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511143(CHEMBL4463305)
Affinity DataKi:  280nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238181(US9394303, 8)
Affinity DataKi:  290nM ΔG°:  -37.3kJ/mole IC50:  1.52E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013868(CHEMBL3265300)
Affinity DataKi:  290nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511139(CHEMBL4454113)
Affinity DataKi:  290nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511122(CHEMBL4452560)
Affinity DataKi:  330nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013862(CHEMBL3265294)
Affinity DataKi:  370nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013863(CHEMBL3265295)
Affinity DataKi:  380nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511122(CHEMBL4452560)
Affinity DataKi:  390nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238192(US9394303, 18)
Affinity DataKi:  490nM ΔG°:  -36.0kJ/mole IC50:  2.54E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  490nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013838(CHEMBL3260042)
Affinity DataKi:  550nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511137(CHEMBL4475729)
Affinity DataKi:  570nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511135(CHEMBL4457901)
Affinity DataKi:  570nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013861(CHEMBL3235895)
Affinity DataKi:  730nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511137(CHEMBL4475729)
Affinity DataKi:  760nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511144(CHEMBL4440719)
Affinity DataKi:  770nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511134(CHEMBL4435041)
Affinity DataKi:  810nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013845(CHEMBL3265290)
Affinity DataKi:  810nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511134(CHEMBL4435041)
Affinity DataKi:  810nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238187(US9394303, 59)
Affinity DataKi:  820nM ΔG°:  -34.7kJ/mole IC50:  4.27E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
Affinity DataKi:  820nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511146(CHEMBL4473975)
Affinity DataKi:  840nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238196(US9394303, 62)
Affinity DataKi:  880nM ΔG°:  -34.6kJ/mole IC50:  4.51E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238184(US9394303, 56)
Affinity DataKi:  900nM ΔG°:  -34.5kJ/mole IC50:  4.68E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511144(CHEMBL4440719)
Affinity DataKi:  900nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511126(CHEMBL4525910)
Affinity DataKi:  950nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511146(CHEMBL4473975)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013882(CHEMBL3265313)
Affinity DataKi:  1.01E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50013844(CHEMBL3235886)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50511126(CHEMBL4525910)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
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