Affinity DataKi: 0.0680nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
TargetRhizopuspepsin(Rhizopus microsporus var. chinensis)
University Of Wisconsin-Madison
Curated by ChEMBL
University Of Wisconsin-Madison
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Compound was evaluated for potency towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]-nicotine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Compound was evaluated for its inhibitory activity against Mevalonate 5-pyrophosphate decarboxylaseMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
TargetRhizopuspepsin(Rhizopus microsporus var. chinensis)
University Of Wisconsin-Madison
Curated by ChEMBL
University Of Wisconsin-Madison
Curated by ChEMBL
Affinity DataKi: 336nMAssay Description:Compound was evaluated for inhibitory activity towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]-nicotine as a radioligan...More data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Compound was evaluated for its inhibitory activity against Mevalonate 5-pyrophosphate decarboxylaseMore data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+3nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
Affinity DataKi: 2.13E+4nMAssay Description:Inhibitory constant against thermolysin.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.450nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration required to inhibit Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitiory activity of the compound against recombinant human cathepsin L (cat L) expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Compound was evaluated for its inhibitory activity against Mevalonate 5-pyrophosphate decarboxylaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
Affinity DataIC50: 10.2nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 11.9nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was evaluated for its inhibitory activity against MevPP decarboxylaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was evaluated for its inhibitory activity against Mevalonate 5-pyrophosphate decarboxylaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals
Curated by ChEMBL
Ariad Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair