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Found 208 with Last Name = 'boovanahalli' and Initial = 'sk'
TargetHistone deacetylase(Homo sapiens (Human))
Kribb

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  110nMAssay Description:Inhibition of HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Kribb

Curated by ChEMBL
LigandPNGBDBM50476373(CHEMBL226224)
Affinity DataIC50:  130nMAssay Description:Inhibition of HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Kribb

Curated by ChEMBL
LigandPNGBDBM50476376(CHEMBL388174)
Affinity DataIC50:  270nMAssay Description:Inhibition of HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Kribb

Curated by ChEMBL
LigandPNGBDBM50475867(CHEMBL214049)
Affinity DataIC50:  350nMAssay Description:Inhibition of HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206613(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50:  350nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206613(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50:  400nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50206624(3-[2-(4-Adamantan-1-yl-phenoxy)-acetylamino]-4-hyd...)
Affinity DataIC50:  400nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430492(CHEMBL2335528)
Affinity DataIC50:  440nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Kribb

Curated by ChEMBL
LigandPNGBDBM50475869(CHEMBL211802)
Affinity DataIC50:  500nMAssay Description:Inhibition of HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430480(CHEMBL2335539)
Affinity DataIC50:  600nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222818(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  600nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Kribb

Curated by ChEMBL
LigandPNGBDBM50475868(CHEMBL213997)
Affinity DataIC50:  670nMAssay Description:Inhibition of HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206600(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50:  700nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  800nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50483784(CHEBI:66517 | CHEMBL1770955)
Affinity DataIC50:  829nMAssay Description:Inhibition of human chymaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222820(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-...)
Affinity DataIC50:  900nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222815(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicot...)
Affinity DataIC50:  900nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222824(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430507(CHEMBL2335563)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222824(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50483785(CHEBI:66518 | CHEMBL1771115)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of human chymaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222817(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430476(CHEMBL2335542)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430481(CHEMBL2335538)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430478(CHEMBL2335540)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Nih

Curated by ChEMBL
LigandPNGBDBM50170983((S)-4-[(S)-4-(R)-Carbamoyl-1-(4-carboxymethoxy-ben...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against Yersinia pestis YopH expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222818(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222827(5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Nih

Curated by ChEMBL
LigandPNGBDBM50170984((S)-4-{(S)-4-(R)-Carbamoyl-1-[4-(carboxy-difluoro-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory concentration against Yersinia pestis YopH expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50095469((5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol |...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222823(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222824(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Nih

Curated by ChEMBL
LigandPNGBDBM50170988((4-{(S)-2-[(S)-3-Benzyloxycarbonylamino-2-(9H-fluo...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory concentration against Yersinia pestis YopH expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430506(CHEMBL2335564)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Nih

Curated by ChEMBL
LigandPNGBDBM50170995((S)-4-[(S)-4-(R)-Carbamoyl-1-(4-carboxymethyl-benz...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory concentration against Yersinia pestis YopH expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222821(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Nih

Curated by ChEMBL
LigandPNGBDBM50170990((S)-4-{(S)-4-(R)-Carbamoyl-1-[4-(carboxy-difluoro-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against Yersinia pestis YopH expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206600(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50400094(CHEMBL427092)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Nih

Curated by ChEMBL
LigandPNGBDBM50170993(CHEMBL364349 | {4-[(S)-2-[3-Benzyloxycarbonylamino...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory concentration against human PTP1B expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430489(CHEMBL2335531)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Nih

Curated by ChEMBL
LigandPNGBDBM50170983((S)-4-[(S)-4-(R)-Carbamoyl-1-(4-carboxymethoxy-ben...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory concentration against human PTP1B expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222818(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isoni...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Rattus norvegicus (rat))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Nih

Curated by ChEMBL
LigandPNGBDBM50170990((S)-4-{(S)-4-(R)-Carbamoyl-1-[4-(carboxy-difluoro-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory concentration against human PTP1B expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Kribb

Curated by ChEMBL
LigandPNGBDBM50476377(CHEMBL226229)
Affinity DataIC50:  3.21E+3nMAssay Description:Inhibition of HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430493(CHEMBL2335527)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222825(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222825(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of hypoxia induced HIF1alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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