Compile Data Set for Download or QSAR
maximum 50k data
Found 161 with Last Name = 'brenner' and Initial = 's'
TargetPro-neuropeptide Y(RAT)
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82286(CAS_59763-91-6 | PP, human | PP,SALMON)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(RAT)
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82300(CAS_59763-91-6 | NSC_41735 | PP, rat)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(Homo sapiens (Human))
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82286(CAS_59763-91-6 | PP, human | PP,SALMON)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(Homo sapiens (Human))
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82297(CAS_59763-91-6 | PP, BOVINE)
Affinity DataKi:  2.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(Homo sapiens (Human))
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82299(PYY Pro34, Human)
Affinity DataKi:  4.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(RAT)
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82299(PYY Pro34, Human)
Affinity DataKi:  7.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252005(2-(3-Benzoylamino-phenyl)-2-oxoethyl ethyl trithio...)
Affinity DataKi:  110nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(Homo sapiens (Human))
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82300(CAS_59763-91-6 | NSC_41735 | PP, rat)
Affinity DataKi:  139nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252371(CHEMBL520279 | Ethyl 2-oxo-2-[1-(phenyl-sulfonyl)-...)
Affinity DataKi:  140nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252319(CHEMBL479602 | Ethyl 2-oxo-2-{5-[(2-Phenoxy-ethylc...)
Affinity DataKi:  460nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(RAT)
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82279(CAS_118997-30-1 | PYY, human)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(RAT)
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-neuropeptide Y(Homo sapiens (Human))
Amgen

Curated by PDSP Ki Database
LigandPNGBDBM82279(CAS_118997-30-1 | PYY, human)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50217137(CHEMBL388710 | Ethyl 2-(4-Methylphenyl)-2-oxoethyl...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50217137(CHEMBL388710 | Ethyl 2-(4-Methylphenyl)-2-oxoethyl...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of HDAC1 in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27493(2-[4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl]-1,...)
Affinity DataIC50:  4.40nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27494(2-[4-(pyridin-2-yl)phenyl]-1,3-diazatricyclo[6.3.1...)
Affinity DataIC50:  15.4nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50251857(CHEMBL481297 | N-Ethyl S-2-(4-acetamidophenyl)-2-o...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataIC50:  19nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27493(2-[4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl]-1,...)
Affinity DataIC50:  20nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27498(10-amino-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13...)
Affinity DataIC50:  22nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252671(2-(4-Acetamidophenyl)-2-oxoethyl dithiopropionate ...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27494(2-[4-(pyridin-2-yl)phenyl]-1,3-diazatricyclo[6.3.1...)
Affinity DataIC50:  28nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27498(10-amino-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13...)
Affinity DataIC50:  32nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  33nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252056(CHEMBL519134 | Ethyl 2-oxo-2-{3-[(pyridine-3-carbo...)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252321(2-(5-(5-Amino-pyrid-2-yl)-thieno-2-yl)-2-oxoethyl ...)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252208(2-(5-Benzylcarbamoyl-thiophen-2-yl)-2-oxoethyl eth...)
Affinity DataIC50:  44nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27496((4Z)-4-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,2,...)
Affinity DataIC50:  45nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
University of Konstanz

LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataIC50:  62nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252005(2-(3-Benzoylamino-phenyl)-2-oxoethyl ethyl trithio...)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27499(1,11b-dihydro-[2H]benzopyrano[4,3,2-de]isoquinolin...)
Affinity DataIC50:  83nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27500(5,6-dihydrophenanthridin-6-one | 5H-Phenanthridin-...)
Affinity DataIC50:  85nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252058(CHEMBL482096 | Ethyl 2-oxo-2-{3-[(quinoline-3-carb...)
Affinity DataIC50:  89nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50251856(CHEMBL481136 | O-Ethyl S-2-(4-Acetamido-phenyl)-2-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252620(CHEMBL487615 | N-Ethyl S-2-(4-Methoxy-phenyl)-2-ox...)
Affinity DataIC50:  94nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252562(2-[4-(2-Acetylamino-ethyl)-phenyl]-2-oxoethyl ethy...)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252007(2-(3-Benzenesulfonylamino-phenyl)-2-oxoethyl ethyl...)
Affinity DataIC50:  104nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252618(2-(4-Methoxyphenyl)-2-oxoethyl Dithiobutyrate | CH...)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252318(CHEMBL479601 | ethyl 2-(5-(2-(4-methoxyphenylamino...)
Affinity DataIC50:  116nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252372(CHEMBL482075 | Ethyl 2-oxo-2-{4-[(quinoline-3-carb...)
Affinity DataIC50:  119nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252667(CHEMBL471044 | N-Ethyl S-2-(4-methoxy-phenyl)-2-ox...)
Affinity DataIC50:  132nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252247(CHEMBL517997 | Ethyl 2-oxo-2-[5-((S)-1-phenyl-ethy...)
Affinity DataIC50:  135nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50251857(CHEMBL481297 | N-Ethyl S-2-(4-acetamidophenyl)-2-o...)
Affinity DataIC50:  141nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM27501(1,5-dihydroxyisoquinoline | CHEMBL338314 | ISQ | i...)
Affinity DataIC50:  151nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252671(2-(4-Acetamidophenyl)-2-oxoethyl dithiopropionate ...)
Affinity DataIC50:  164nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252248(CHEMBL510856 | Ethyl 2-oxo-2-[5-((R)-1-Phenyl-ethy...)
Affinity DataIC50:  165nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252317(2-[5-(4-Methoxy-benzylcarbamoyl-methyl)-thiophen-2...)
Affinity DataIC50:  175nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252006(CHEMBL482280 | Ethyl 2-oxo-2{-[(1-phenyl-methanoyl...)
Affinity DataIC50:  175nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 161 total ) | Next | Last >>
Jump to: