Compile Data Set for Download or QSAR
maximum 50k data
Found 107 with Last Name = 'bryk' and Initial = 'r'
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119876(SL932 | US9073941, 503)
Affinity DataKi:  37nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119876(SL932 | US9073941, 503)
Affinity DataKi:  78nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119877(SL809 | US9073941, 502)
Affinity DataKi:  93nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119878(SL827 | US9073941, 500)
Affinity DataKi:  140nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119880(SL418)
Affinity DataKi:  143nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119877(SL809 | US9073941, 502)
Affinity DataKi:  155nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119878(SL827 | US9073941, 500)
Affinity DataKi:  155nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119879(SL917 | US9073941, 505)
Affinity DataKi:  233nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119879(SL917 | US9073941, 505)
Affinity DataKi:  289nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119880(SL418)
Affinity DataKi:  333nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347871(CHEMBL1802618)
Affinity DataKi:  3.40E+3nMAssay Description:Competitive inhibition of human recombinant PKRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347876(CHEMBL1802782)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347891(CHEMBL1802629)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119881(K906-3584)
Affinity DataIC50: <100nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347926(CHEMBL1802778)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50173832(4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylme...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50230828(5-(4-fluorophenyl)-2-ureidothiophene-3-carboxamide...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347887(CHEMBL1802769)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347889(CHEMBL1802630)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM7401((2 Z,3 E)-6-Bromoindirubin-3 -oxime | (3E)-6-bromo...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM92887(Triazaspirobenzyl, 5)
Affinity DataIC50:  650nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347920(CHEMBL1802486)
Affinity DataIC50:  750nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM92887(Triazaspirobenzyl, 5)
Affinity DataIC50:  900nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347927(CHEMBL1802623)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347902(CHEMBL1802616)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM92887(Triazaspirobenzyl, 5)
Affinity DataIC50:  1.50E+3nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347886(CHEMBL1802771)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM6878(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n ...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM92887(Triazaspirobenzyl, 5)
Affinity DataIC50:  2.00E+3nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347924(CHEMBL1802728)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM92888(Triazaspirobenzyl, 4)
Affinity DataIC50:  2.00E+3nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM92887(Triazaspirobenzyl, 5)
Affinity DataIC50:  2.00E+3nMAssay Description:Enzymatic assay using Lpd.More data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347905(CHEMBL1802613)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347885(CHEMBL1802773)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347916(CHEMBL1802488)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50073765(CHEMBL367625 | N*2*-((1R,2S)-2-Amino-cyclohexyl)-N...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347875(CHEMBL1802783)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347923(CHEMBL1802729)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347918(CHEMBL1502303)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM7238((3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-2,3...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50298223(CGP-57380 | CHEMBL1240885 | CHEMBL576817 | N-(4-fl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM6860(6-bromo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119889(4031-0653)
Affinity DataIC50:  6.00E+3nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM7534(1H-pyrazolo[3,4-b]quinoxalin-3-amine | pyrazolo[3,...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347922(CHEMBL270724)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347879(CHEMBL1802779)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM16018(14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexa...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM6877(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3m ...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50347883(CHEMBL1802774)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 107 total ) | Next | Last >>
Jump to: