Compile Data Set for Download or QSAR
maximum 50k data
Found 48 with Last Name = 'constantine' and Initial = 'kl'
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192462((S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxy...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192463(2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid | ...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192465(2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-methoxyacet...)
Affinity DataKi:  9nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192463(2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid | ...)
Affinity DataKi:  16nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192462((S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxy...)
Affinity DataKi:  33nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192465(2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-methoxyacet...)
Affinity DataKi:  50nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192464(1-(2,3-bis(2-chlorobenzyloxy)phenyl)ethane-1,2-dio...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50192464(1-(2,3-bis(2-chlorobenzyloxy)phenyl)ethane-1,2-dio...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human recombinant MK2 expressed in Escherichia coli BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50253633(2-(2-styrylpyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant MK2 expressed in Escherichia coli BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301952((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at GIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301952((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at PTHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301952((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at GIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301952((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at glucagon receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301952((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at PTHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylneuraminate-9-phosphatase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50436923(CHEMBL2402022)
Affinity DataIC50:  1.10E+4nMAssay Description:Reversible inhibition of recombinant HDHD4 (unknown origin) using Neu5Ac-9-P as substrate assessed as release of phosphate after 30 mins by maiachite...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylneuraminate-9-phosphatase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50436926(CHEMBL2402114)
Affinity DataIC50:  4.98E+4nMAssay Description:Inhibition of recombinant HDHD4 (unknown origin) using Neu5Ac-9-P as substrate assessed as release of phosphate after 30 mins by maiachite green assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50240538(CHEMBL57481 | Isoquinolin-5-ol)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of human recombinant MK2 expressed in Escherichia coli BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylneuraminate-9-phosphatase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50436925(CHEMBL3037907)
Affinity DataIC50:  9.37E+4nMAssay Description:Inhibition of recombinant HDHD4 (unknown origin) using Neu5Ac-9-P as substrate assessed as release of phosphate after 30 mins by maiachite green assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM23450(1-Naphthalenol | 1-Naphthol | CHEMBL122617 | Napht...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MK2 expressed in Escherichia coli BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylneuraminate-9-phosphatase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50436924(CHEMBL2402116)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDHD4 (unknown origin) using Neu5Ac-9-P as substrate assessed as release of phosphate after 30 mins by maiachite green assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301936((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  215nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301937((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301938((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301939((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301940((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  148nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301941((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  87nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301942((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  95nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301943((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301944((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301945((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  93nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301946((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301947((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  965nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301948((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301949(CHEMBL583264)
Affinity DataEC50:  0.0340nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301950((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301951((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301952((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataEC50:  0.0870nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301953((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataEC50:  0.0930nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301932((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301931((4S)-4-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-5-yl)p...)
Affinity DataEC50:  545nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Mus musculus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301952((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at mouse GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Mus musculus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301953((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at mouse GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKd:  802nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301952((3S,6S,9S,12S,15S,21S)-21-(2-((S)-2-amino-3-(1H-im...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at glucagon receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301933((2S,5S,9S,12S,15S,18S,21S,27S)-27-((S)-2-((S)-2-am...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301934((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  787nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50301935((3S,6S,9S,12S,15S,21S)-21-((S)-2-((S)-2-amino-3-(1...)
Affinity DataEC50:  480nMAssay Description:Agonist activity at human GLP1R expressed in CHO cells assessed as stimulation of intracellular [3H]cAMP accumulation after 30 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed