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Target
Fatty acid-binding protein 5
Ligand
BDBM50192462
Substrate
n/a
Meas. Tech.
ChEMBL_381686 (CHEMBL869162)
Ki
33±n/a nM
Citation
 McDonnell, PA; Constantine, KL; Goldfarb, V; Johnson, SR; Sulsky, R; Magnin, DR; Robl, JA; Caulfield, TJ; Parker, RA; Taylor, DS; Adam, LP; Metzler, WJ; Mueller, L; Farmer, BT NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein. J Med Chem 49:5013-7 (2006) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein 5
Synonyms:
FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5)
Type:
Enzyme
Mol. Mass.:
15164.79
Organism:
Homo sapiens (Human)
Description:
Q01469
Residue:
135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE
  
Inhibitor
Name:
BDBM50192462
Synonyms:
(S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxyacetic acid | CHEMBL378857
Type:
Small organic molecule
Emp. Form.:
C22H18Cl2O5
Mol. Mass.:
433.281
SMILES:
O[C@H](C(O)=O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl
Structure:
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