TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 106nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 106nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 341nMAssay Description:Inhibition of muscarinic acetylcholine receptor M1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 865nMAssay Description:Inhibition of muscarinic acetylcholine receptor M4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 890nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 4.01E+3nMAssay Description:Inhibition of muscarinic acetylcholine receptor M2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.50E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 9.00E+3nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >3.30E+4nMAssay Description:Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting methodMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.00800nMAssay Description:Displacement of [33P]-SIP from human recombinant S1P1 expressed in CHO cell membranes measured after 45 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.00800nMAssay Description:Displacement of [33P]-SIP from human recombinant S1P1 expressed in CHO cell membranes measured after 45 mins by radioligand competitive binding analy...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Displacement of 33-P-S1P from from human S1P receptor expressed in CHO cell membranes after 50 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Displacement of [33P]-SIP from human recombinant S1P1 expressed in CHO cell membranes measured after 45 mins by radioligand competitive binding analy...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Displacement of [33P]-SIP from human recombinant S1P1 expressed in CHO cell membranes measured after 45 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.0140nMAssay Description:Displacement of [33P]-SIP from human recombinant S1P1 expressed in CHO cell membranes measured after 45 mins by radioligand competitive binding analy...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.0140nMAssay Description:Displacement of 33-P-S1P from from human S1P receptor expressed in CHO cell membranes after 50 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.0160nMAssay Description:Displacement of [33P]-SIP from human recombinant S1P1 expressed in CHO cell membranes measured after 45 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Displacement of [33P]-SIP from human recombinant S1P1 expressed in CHO cell membranes measured after 45 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Displacement of [33P]S1P from human S1P1 expressed in CHO cell membranes measured after 45 mins by TopCount methodMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Displacement of [33P]S1P from human S1P1 expressed in CHO cell membranes measured after 45 mins by TopCount methodMore data for this Ligand-Target Pair