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Found 39 with Last Name = 'derimay' and Initial = 'n'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134434(CHEMBL3746046)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134433(CHEMBL3745968)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134432(CHEMBL3747036)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134429(CHEMBL3746964)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134428(CHEMBL3746007)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134393(CHEMBL3746464)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134434(CHEMBL3746046)
Affinity DataIC50:  5nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134430(CHEMBL3747248)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134431(CHEMBL3747181)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134394(CHEMBL3747325)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134391(CHEMBL3747090)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134433(CHEMBL3745968)
Affinity DataIC50:  8nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134389(CHEMBL3747338)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134390(CHEMBL3747602)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134392(CHEMBL3747423)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134429(CHEMBL3746964)
Affinity DataIC50:  130nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134386(CHEMBL3747655)
Affinity DataIC50:  165nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134393(CHEMBL3746464)
Affinity DataIC50:  243nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134430(CHEMBL3747248)
Affinity DataIC50:  270nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134432(CHEMBL3747036)
Affinity DataIC50:  480nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134431(CHEMBL3747181)
Affinity DataIC50:  507nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134428(CHEMBL3746007)
Affinity DataIC50:  629nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50491985(CHEMBL2391620)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134391(CHEMBL3747090)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134390(CHEMBL3747602)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134387(CHEMBL3747623)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134392(CHEMBL3747423)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134394(CHEMBL3747325)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134386(CHEMBL3747655)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant PDE3 by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134388(CHEMBL3747039)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134387(CHEMBL3747623)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134386(CHEMBL3747655)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134388(CHEMBL3747039)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134389(CHEMBL3747338)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM74351(MLS001360529 | SMR001223863 | cid_3694944)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50234316(CHEMBL2391621)
Affinity DataIC50:  3.94E+4nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50491987(CHEMBL2391618)
Affinity DataIC50:  1.57E+5nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50491984(CHEMBL2391619)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50491986(CHEMBL2391615)
Affinity DataIC50:  4.91E+5nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed