Compile Data Set for Download or QSAR
maximum 50k data
Found 279 with Last Name = 'dias' and Initial = 'r'
LigandPNGBDBM50182468(4,6,2'-Trifluoro-5'-[3-(1-hydroxy-1-methyl-ethyl)-...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50182464(2',4-difluoro-5'-[3-(trifluoromethyl)imidazo[1,2-b...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50179995(3'-(7-methyl-imidazo[1,2-a]pyrimidin-3-yl)-bipheny...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50179995(3'-(7-methyl-imidazo[1,2-a]pyrimidin-3-yl)-bipheny...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50179996(4,2'-difluoro-5'-(7-trifluoromethyl-imidazo[1,2-a]...)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50179855(6,2'-Difluoro-5'-[3-(1-hydroxy-1-methyl-ethyl)-imi...)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182464(2',4-difluoro-5'-[3-(trifluoromethyl)imidazo[1,2-b...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50179849(2-(3-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182468(4,6,2'-Trifluoro-5'-[3-(1-hydroxy-1-methyl-ethyl)-...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50179855(6,2'-Difluoro-5'-[3-(1-hydroxy-1-methyl-ethyl)-imi...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha5 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50179996(4,2'-difluoro-5'-(7-trifluoromethyl-imidazo[1,2-a]...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182467(3'-(3-methyl-imidazo[1,2-b][1,2,4]triazin-7-yl)bip...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50182465(4,2'-difluoro-5'-[3-(1-hydroxy-1-methyl-ethyl)imid...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50182467(3'-(3-methyl-imidazo[1,2-b][1,2,4]triazin-7-yl)bip...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50179855(6,2'-Difluoro-5'-[3-(1-hydroxy-1-methyl-ethyl)-imi...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50179855(6,2'-Difluoro-5'-[3-(1-hydroxy-1-methyl-ethyl)-imi...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha3 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50180005(1-(1-(3-(pyridin-3-yl)phenyl)-1H-benzo[d]imidazol-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182465(4,2'-difluoro-5'-[3-(1-hydroxy-1-methyl-ethyl)imid...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50179999(3'-(7-methyl-imidazo[1,2-a]pyridin-3-yl)-biphenyl-...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50179849(2-(3-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50179999(3'-(7-methyl-imidazo[1,2-a]pyridin-3-yl)-biphenyl-...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50182466(3'-(7-methyl-imidazo[1,2-b]pyridazin-3-yl)-bipheny...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50180005(1-(1-(3-(pyridin-3-yl)phenyl)-1H-benzo[d]imidazol-...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50182466(3'-(7-methyl-imidazo[1,2-b]pyridazin-3-yl)-bipheny...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  33nMAssay Description:Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universidade Federal Fluminense

Curated by ChEMBL
LigandPNGBDBM50154254(CHEMBL3775705)
Affinity DataKi:  120nMAssay Description:Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universidade Federal Fluminense

Curated by ChEMBL
LigandPNGBDBM50154252(CHEMBL3774934)
Affinity DataKi:  130nMAssay Description:Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universidade Federal Fluminense

Curated by ChEMBL
LigandPNGBDBM50154253(CHEMBL3775377)
Affinity DataKi:  130nMAssay Description:Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Universidade Federal Fluminense

Curated by ChEMBL
LigandPNGBDBM50205620(CHEMBL3943212)
Affinity DataKi:  3.10E+3nMAssay Description:Competitive inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347344(CHEMBL1801156)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347344(CHEMBL1801156)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347344(CHEMBL1801156)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347349(CHEMBL1801161)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347349(CHEMBL1801161)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347349(CHEMBL1801161)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347343(CHEMBL1801155)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347343(CHEMBL1801155)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347343(CHEMBL1801155)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347345(CHEMBL1801157)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347345(CHEMBL1801157)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347345(CHEMBL1801157)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347348(CHEMBL1801160)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347348(CHEMBL1801160)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347348(CHEMBL1801160)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347335(CHEMBL1801068)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50232731(2-{3'-[6-(1-methanesulfonyl-1-methyl-ethyl)-quinol...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50232731(2-{3'-[6-(1-methanesulfonyl-1-methyl-ethyl)-quinol...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50232731(2-{3'-[6-(1-methanesulfonyl-1-methyl-ethyl)-quinol...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50347335(CHEMBL1801068)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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