TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 2.70E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 3.30E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.48E+4nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 8.70E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 4.20E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition of TPA-induced AP-1 activity expressed in human HEK293T cells treated 1 hr before TPA challenge measured after 18 hrs by FRET based beta-l...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIF2alpha in human 786-0 cells expresseing truncated HIF1alpha assessed as reduction in luciferase activity after 24 hrs by reporter ge...More data for this Ligand-Target Pair
Affinity DataEC50: 1.49E+3nMAssay Description:Inhibition of TPA-induced AP-1 activity expressed in human HEK293T cells treated 1 hr before TPA challenge measured after 18 hrs by FRET based beta-l...More data for this Ligand-Target Pair