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Found 50 with Last Name = 'dracínský' and Initial = 'm'
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50439836(CHEMBL2420072)
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant human HGPRT expressed in Escherichia coli Sphi606 cells by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50049966(CHEMBL177948 | [4-(2-Amino-6-oxo-1,6-dihydro-purin...)
Affinity DataKi:  400nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360117(CHEMBL1928784)
Affinity DataKi:  500nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50039559(CHEMBL267803 | [5-(2-Amino-6-oxo-1,6-dihydro-purin...)
Affinity DataKi:  500nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50439833(CHEMBL2420080)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of recombinant human HGPRT expressed in Escherichia coli Sphi606 cells by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360122(CHEMBL1928777)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360116(CHEMBL1928783)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360109(CHEMBL1928778)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50439834(CHEMBL2420081)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of recombinant human HGPRT expressed in Escherichia coli Sphi606 cells by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50361442(CHEMBL1934407)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human HGPRT by spectrophotometric analysis in absence of PPiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50439835(CHEMBL2420071)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition of recombinant human HGPRT expressed in Escherichia coli Sphi606 cells by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50361443(CHEMBL1934409)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human HGPRT by spectrophotometric analysis in absence of PPiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50049962(CHEMBL172844 | [7-(2-Amino-6-oxo-1,6-dihydro-purin...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50439832(CHEMBL2420078)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of recombinant human HGPRT expressed in Escherichia coli Sphi606 cells by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360112(CHEMBL19784)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360119(CHEMBL1928930)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360114(CHEMBL20283)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360115(CHEMBL1928782)
Affinity DataKi:  5.60E+4nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360118(CHEMBL1928785)
Affinity DataKi:  7.70E+4nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360121(CHEMBL1928776)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360120(CHEMBL1928931)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360108(CHEMBL1928775)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50039555(CHEMBL13130 | [5-(6-Oxo-1,6-dihydro-purin-9-yl)-pe...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360110(CHEMBL1928779)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360111(CHEMBL1928780)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50360113(CHEMBL1928781)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50:  0.508nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM19214((1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydro...)
Affinity DataIC50:  9.27nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  10.7nMAssay Description:Antagonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity after 18 hrs by lu...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  21.0nMAssay Description:Antagonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity after 18 hrs by l...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataIC50:  3.13E+3nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataIC50:  3.81E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417030(CHEMBL1257167)
Affinity DataIC50:  5.14E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417022(CHEMBL1258783)
Affinity DataIC50:  1.36E+4nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  2.77nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417022(CHEMBL1258783)
Affinity DataEC50:  9.95E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417027(CHEMBL1256103)
Affinity DataEC50:  1.03E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417029(CHEMBL1257168)
Affinity DataEC50:  4.03E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417025(CHEMBL1257284)
Affinity DataEC50:  1.66E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM19214((1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydro...)
Affinity DataEC50:  0.338nMAssay Description:Agonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity aft...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417024(CHEMBL1256102)
Affinity DataEC50:  2.08E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  0.458nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417028(CHEMBL1258902)
Affinity DataEC50:  485nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417030(CHEMBL1257167)
Affinity DataEC50:  403nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataEC50:  35.5nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417029(CHEMBL1257168)
Affinity DataEC50:  5.19E+3nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417028(CHEMBL1258902)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417027(CHEMBL1256103)
Affinity DataEC50:  52nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417026(CHEMBL1256105)
Affinity DataEC50:  6.73nMAssay Description:Agonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataEC50:  129nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed