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Found 19 with Last Name = 'dreyfus' and Initial = 'n'
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458383(1-(2-(((3R,5S)-1-((6-fluoro-2-methylbenzo[d]thiazo...)
Affinity DataIC50:  0.214nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458383(1-(2-(((3R,5S)-1-((6-fluoro-2-methylbenzo[d]thiazo...)
Affinity DataIC50:  0.214nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458387(1-[2-[(3R,5S)-1-[(1S)-1-(6-fluoro-2-methyl-1,3-ben...)
Affinity DataIC50:  0.385nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458387(1-[2-[(3R,5S)-1-[(1S)-1-(6-fluoro-2-methyl-1,3-ben...)
Affinity DataIC50:  0.385nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458382(1-(2-(((3R,5S)-1-((6-fluoro-2-methylbenzo[d]thiazo...)
Affinity DataIC50:  0.465nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458382(1-(2-(((3R,5S)-1-((6-fluoro-2-methylbenzo[d]thiazo...)
Affinity DataIC50:  0.465nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458386(1-[2-[(3R,5S)-1-[(1S)-1-(6-fluoro-2-methyl-1,3-ben...)
Affinity DataIC50:  0.495nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458386(1-[2-[(3R,5S)-1-[(1S)-1-(6-fluoro-2-methyl-1,3-ben...)
Affinity DataIC50:  0.495nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458385(1-[3-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiaz...)
Affinity DataIC50:  0.592nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458385(1-[3-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiaz...)
Affinity DataIC50:  0.592nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458384(1-[6-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiaz...)
Affinity DataIC50:  0.782nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM458384(1-[6-[(3R,5S)-1-[(6-fluoro-2-methyl-1,3-benzothiaz...)
Affinity DataIC50:  0.782nMAssay Description:The OGA enzyme catalyses the removal of O-GlcNAc from nucleocytoplasmic proteins. To measure this activity Fluorescein di-N-acetyl-β-N-acetyl-D-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM532950((?)-5-fluoro-6-[1-[4-(5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  1.13nMAssay Description:The assay buffer is prepared to give a final concentration of 50 mM H2NaPO3—HNa2PO3, 0.01% bovine serum albumin and 0.01% Triton™ X-100 in water, at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM532948((?)-6-[1-[4-(5-methyl-1,3,4-oxadiazol-2-yl)-1-pipe...)
Affinity DataIC50:  1.24nMAssay Description:The assay buffer is prepared to give a final concentration of 50 mM H2NaPO3—HNa2PO3, 0.01% bovine serum albumin and 0.01% Triton™ X-100 in water, at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM532951((+)-6-[(1R)-1-[4-(5-methyl-1,3,4-oxadiazol-2-yl)-1...)
Affinity DataIC50:  611nMAssay Description:The assay buffer is prepared to give a final concentration of 50 mM H2NaPO3—HNa2PO3, 0.01% bovine serum albumin and 0.01% Triton™ X-100 in water, at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM532952((+)-5-fluoro-6-[1-[4-(5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  2.66E+3nMAssay Description:The assay buffer is prepared to give a final concentration of 50 mM H2NaPO3—HNa2PO3, 0.01% bovine serum albumin and 0.01% Triton™ X-100 in water, at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50434279(CHEMBL2386162)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50434279(CHEMBL2386162)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50434279(CHEMBL2386162)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed