Affinity DataKi: 4.60E+5nMAssay Description:Non-competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate h...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Competitive type of inhibition of human 5'-nucleotidase using IMP as substrate assessed as inhibitor constant for free enzyme by Lineweaver-Burk plot...More data for this Ligand-Target Pair
Affinity DataKi: 5.36E+5nMAssay Description:Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by...More data for this Ligand-Target Pair
Affinity DataKi: 5.82E+5nMAssay Description:Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
Affinity DataKi: 7.90E+5nMAssay Description:Non-competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate h...More data for this Ligand-Target Pair
Affinity DataKi: 8.43E+5nMAssay Description:Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
Affinity DataKi: 8.93E+5nMAssay Description:Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
Affinity DataKi: 9.00E+5nMAssay Description:Non-competitive type of inhibition of human 5'-nucleotidase using IMP as substrate assessed as inhibitor constant for enzyme substrate complex by Lin...More data for this Ligand-Target Pair
Affinity DataKi: 9.50E+5nMAssay Description:Competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate hydro...More data for this Ligand-Target Pair
Affinity DataKi: 9.50E+5nMAssay Description:Competitive inhibition of 5'-nucleotidase (unknown origin) using varying level of IMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.95E+5nMAssay Description:Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+6nMAssay Description:Competitive inhibition of 5'-nucleotidase (unknown origin) using varying level of IMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.35E+6nMAssay Description:Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal...More data for this Ligand-Target Pair
Affinity DataKi: 1.48E+6nMAssay Description:Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by...More data for this Ligand-Target Pair
Affinity DataKi: 1.65E+6nMAssay Description:Non-competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate h...More data for this Ligand-Target Pair
Affinity DataKi: 1.65E+6nMAssay Description:Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+6nMAssay Description:Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+6nMAssay Description:Competitive inhibition of 5'-nucleotidase (unknown origin) using varying level of IMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+6nMAssay Description:Inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate hydrolysis by rap...More data for this Ligand-Target Pair
Affinity DataKi: 2.43E+6nMAssay Description:Competitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
Affinity DataKi: 2.43E+6nMAssay Description:Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for free enzyme using varying level of IMP as substrate by...More data for this Ligand-Target Pair
Affinity DataKi: 2.44E+6nMAssay Description:Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal...More data for this Ligand-Target Pair
Affinity DataKi: 2.52E+6nMAssay Description:Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana...More data for this Ligand-Target Pair
Affinity DataKi: 2.78E+6nMAssay Description:Competitive inhibition of recombinant N-terminal truncated human cytosolic 5'-nucleotidase-2 assessed as inhibition of inosine 5'-monophosphate hydro...More data for this Ligand-Target Pair
Affinity DataKi: 3.36E+6nMAssay Description:Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana...More data for this Ligand-Target Pair
Affinity DataKi: 4.98E+6nMAssay Description:Uncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot anal...More data for this Ligand-Target Pair
Affinity DataKi: 6.27E+6nMAssay Description:Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for enzyme substrate complex using varying level of IMP as...More data for this Ligand-Target Pair
Affinity DataKi: 6.97E+6nMAssay Description:Noncompetitive inhibition of recombinant cN-II (unknown origin) using varying level of IMP as substrate by HPLC method based Lineweaver-Burk plot ana...More data for this Ligand-Target Pair
Affinity DataKi: 1.13E+7nMAssay Description:Mixed type inhibition of recombinant cN-II (unknown origin) assessed as inhibitor constant for enzyme substrate complex using varying level of IMP as...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PI3KCdelta/PIK3R1 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of PI3KCgamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of PI3KCdelta/PIK3R1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in bovine anterior pituitary membrane using [3H]dihydroergocriptine as the radioli...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of PI3KCbeta/PIK3R1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in bovine anterior pituitary membrane using [3H]dihydroergocriptine as the radioli...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant CD73 (27 to 549 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells assessed as reduction in conv...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH3T3 cells assessed as inhibition of drug efflux by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of CD73 in human NCI-H292 cells assessed as reduction in conversion of AMP to adenosine incubated for 30 mins by malachite green reagent b...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligandMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of PI3KCgamma (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in bovine anterior pituitary membrane using [3H]dihydroergocriptine as the radioli...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of PI3KCalpha/PIK3R1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in bovine anterior pituitary membrane using [3H]dihydroergocriptine as the radioli...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligandMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Inserm 1052/Cnrs 5286/University Of Lyon
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of PI3KCbeta/PIK3R1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH3T3 cells assessed as inhibition of drug efflux by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity towards dopamine receptor was determined in rat striatal membrane using [3H]spiroperidol as the radioligandMore data for this Ligand-Target Pair