Compile Data Set for Download or QSAR
maximum 50k data
Found 228 with Last Name = 'fukushima' and Initial = 'k'
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM85740(Dysiherbaine)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]kianic acid from recombinant GluK1 kainate receptor (unknown origin) expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Yokohama City University

Curated by ChEMBL
LigandPNGBDBM85740(Dysiherbaine)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]kianic acid from recombinant GluK2 kainate receptor (unknown origin) expressed in HEK293 cell membranes measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149846(2''-Amino-6''-(2-cyclopropylmethoxy-6-hydroxy-phen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196700(5-((3-(3-(prop-1-en-2-yl)benzyl)cyclohexyl)methyl)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196694(CHEMBL225166 | N-(1-(thiophen-3-ylmethyl)piperidin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149839(2''-Amino-6''-(2-cyclobutylmethoxy-6-hydroxy-pheny...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149832(2''-Amino-6''-(2-hydroxy-6-propoxy-phenyl)-1,2,3,4...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196718(CHEMBL373512 | N-(1-(thiophen-2-ylmethyl)piperidin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149833(2''-Amino-6''-(2-hydroxy-6-isobutoxy-phenyl)-1,2,3...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149838(2''-Amino-6''-(2-hydroxy-6-pentyloxy-phenyl)-1,2,3...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289610(CHEMBL44717 | [3-(4,5,7-Trifluoro-benzothiazol-2-y...)
Affinity DataIC50:  6.60nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289614(CHEMBL288748 | [3-Chloro-5-(4,5,7-trifluoro-benzot...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289613(CHEMBL44743 | {Phenyl-[3-(4,5,7-trifluoro-benzothi...)
Affinity DataIC50:  8.30nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289624(CHEMBL44780 | {Phenyl-[3-(4,5,7-trifluoro-benzothi...)
Affinity DataIC50:  8.40nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149825(2-Amino-6-(2-cyclopropylmethoxy-6-hydroxy-phenyl)-...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289628(3-Carboxymethyl-5-(4,5,7-trifluoro-benzothiazol-2-...)
Affinity DataIC50:  8.70nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289617(CHEMBL47614 | [3-Fluoro-5-(4,5,7-trifluoro-benzoth...)
Affinity DataIC50:  8.80nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196692(CHEMBL388516 | N-(1-(4-methylbenzyl)piperidin-3-yl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149843(2''-Amino-6''-(2-benzyloxy-6-hydroxy-phenyl)-1,2,3...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289616(CHEMBL45751 | [2-Chloro-3-(4,5,7-trifluoro-benzoth...)
Affinity DataIC50:  9.30nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289621(CHEMBL46074 | [3-Bromo-5-(4,5,7-trifluoro-benzothi...)
Affinity DataIC50:  9.40nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289629(CHEMBL47646 | [3-Oxo-4-(4,5,7-trifluoro-benzothiaz...)
Affinity DataIC50:  9.5nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289612(CHEMBL46170 | [3-Methyl-5-(4,5,7-trifluoro-benzoth...)
Affinity DataIC50:  9.60nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289625(CHEMBL43995 | {Benzyl-[3-(4,5,7-trifluoro-benzothi...)
Affinity DataIC50:  9.70nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196690(CHEMBL224535 | N-(1-(4-aminobenzyl)piperidin-3-yl)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196711(1-benzyl-3-piperidyl-(1H-5-indazolyl)ether | 5-(1-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196695(CHEMBL224510 | N-(1-(3,4-difluorobenzyl)piperidin-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289615(CHEMBL45290 | [3-Iodo-5-(4,5,7-trifluoro-benzothia...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289620(CHEMBL442690 | {Methyl-[3-(4,5,7-trifluoro-benzoth...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196689(CHEMBL224166 | N-(1-((1H-pyrrol-2-yl)methyl)piperi...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196682(CHEMBL426925 | N-(1-(4-chlorobenzyl)piperidin-3-yl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149828(2-Amino-6-(2-cyclobutylmethoxy-6-hydroxy-phenyl)-1...)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM16496(2-{3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289619(CHEMBL542104 | [3-Dimethylamino-5-(4,5,7-trifluoro...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289623(CHEMBL296769 | {Methyl-[3-(4,5,7-trifluoro-benzoth...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196707(CHEMBL390837 | N-(1-(2-chlorobenzyl)piperidin-3-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149831(2''-Amino-6''-(2-heptyloxy-6-hydroxy-phenyl)-1,2,3...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149852(2''-Amino-6''-(2-ethoxy-6-hydroxy-phenyl)-1,2,3,4,...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149850(2-Amino-6-(2-butoxy-6-hydroxy-phenyl)-1'',2'',3'',...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149837(2-Amino-6-(2-hydroxy-6-isobutoxy-phenyl)-1'',2'',3...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149842(2''-Amino-6''-(2,6-dihydroxy-phenyl)-1,2,3,4,5,6-h...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196712(CHEMBL225637 | N-(1-(4-methoxybenzyl)piperidin-3-y...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  16nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196704(1-benzyl-N-(1H-5-indazolyl)piperidine-3-carboxamid...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50239947(CHEMBL4089730 | US20230303494, Compound BMS202 | U...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Ig-tagged human PD1/His-tagged human PDL1 interaction incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50289626(CHEMBL297861 | [2-(4,5,7-Trifluoro-benzothiazol-2-...)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196728(CHEMBL389168 | N-(1-(3-chlorobenzyl)piperidin-3-yl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196725(CHEMBL224885 | N-(1-benzyl-3-piperidyl)-N-(1H-5-in...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1/2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50196687(1-(2,6-dichlorobenzyl)-3-(1H-indazol-5-yl)urea | 1...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyoto 619-0216

Curated by ChEMBL
LigandPNGBDBM50149826(2-Amino-6-(2-hydroxy-6-pentyloxy-phenyl)-1'',2'',3...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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