TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.00000600nMAssay Description:Displacement of [3H]GW0385 from HIV1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.0000150nMAssay Description:Displacement of [3H]GW0385 from HIV1 proteaseMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataKi: 0.460nMAssay Description:Antagonist activity at 5HT2A receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
Affinity DataKi: <2nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: <2nM ΔG°: <-50.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Antagonist activity at 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -49.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -49.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -48.7kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -48.7kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -48.2kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -48.2kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -45.8kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 15nM ΔG°: -45.4kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]histamine human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:In vitro binding affinity towards human Estrogen receptor 2 using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair