TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at Opioid receptor delta 1 by displacing [3H]- DSLETMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at Opioid receptor delta 1 by displacing [3H]- DSLETMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at opioid receptor mu by displacing [3H]- DAMGOMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of Adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataKi: 2.02E+3nMAssay Description:In Vitro evaluation for the binding affinity in homogenates of rat brain at opioid receptor mu by displacing [3H]- DAMGOMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.0450nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.920nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding ability towards opioid receptor delta expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of DGAT1 in human HuTu80 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding ability towards opioid receptor kappa expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of DGAT1 in human adipose tissue assessed as reduction in triacylglycerol synthesisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding ability towards opioid receptor delta expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 12.3nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 17.5nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Binding ability towards opioid receptor delta expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 23.7nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 23.7nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 28.6nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Binding ability towards opioid receptor delta expressed in homogenates of rat brain.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Displacement of [3H]-DSLET from rat brain membrane delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of DGAT1 in dog liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillographyMore data for this Ligand-Target Pair