Found 192 with Last Name = 'higgins' and Initial = 'j' 
Affinity DataKi: 0.000600nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET ultra assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.000930nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET ultra assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.00239nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET ultra assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.00736nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.00813nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET ultra assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.00826nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.00940nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET ultra assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0114nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0370nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: >0.129nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: >0.129nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: >0.129nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: >0.129nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: >0.129nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET plus assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Inhibition of human PCSK9 using Alexa Fluor 674 as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
3D Structure (crystal)TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human MDR1 expressed in HEK cells assessed as [3H]vinblastine transport after 2.5 mins by scintillation countMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
