BDBM50050937 (S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid::CHEMBL267179::N-formyl-methionyl-leucyl-phenylalanine::N-formylmethionine-leucine-phenylalanine

SMILES CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=PRQROPMIIGLWRP-BZSNNMDCSA-N

Data  1 KI  1 IC50  3 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50050937   

TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-fMLP from FPR in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataEC50:  20nMAssay Description:Agonistic activity was determined by measuring the ability to induce superoxide production(as measured by reduction of cytochrome C) using human neut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at FPR1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataEC50:  2.04E+4nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFormyl peptide receptor-related sequence 1(Mus musculus)
Sorbonne University

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataKd: >300nMAssay Description:Binding affinity to mouse FPR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataKd: >300nMAssay Description:Binding affinity to human FPR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataKd:  3nMAssay Description:Binding affinity to human FPR1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataIC50:  20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 3(Homo sapiens (Human))
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at FPRL2 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed