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Found 127 with Last Name = 'hirayama' and Initial = 'f'
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358251(CHEMBL1922344)
Affinity DataKi:  20nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi:  31nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic substrate S2302 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358251(CHEMBL1922344)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic substrate S2302 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human thrombin using chromogenic substrate S2238 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358251(CHEMBL1922344)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human thrombin using chromogenic substrate S2238 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50042002(CHEMBL3359576)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50042001(CHEMBL3359575)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50035155(CHEMBL3354239)
Affinity DataIC50:  4nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50035154(CHEMBL3354240)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50035158(CHEMBL3354236)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041996(CHEMBL3359570)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209900(3-(({7-[amino(imino)methyl]-2-naphthyl}methyl)-{1-...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50035157(CHEMBL3354237)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50042000(CHEMBL3359574)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209891(CHEMBL390266 | [(((E)-3-{3-[amino(imino)methyl]phe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209893(7-({[1-(2,5-dimethoxy-benzenesulfonyl)-piperidin-4...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209895(CHEMBL244221 | N-({7-[amino(imino)methyl]-2-naphth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209899(3-(((E)-3-{3-[amino(imino)methyl]phenyl}prop-2-en-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209904(CHEMBL244436 | [(({7-[amino(imino)methyl]-2-naphth...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50035156(CHEMBL3354238)
Affinity DataIC50:  15nMAssay Description:Inhibition of purified factor 10a (unknown origin) using chromogenic substrate S-2222 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041999(CHEMBL3359573)
Affinity DataIC50:  16nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358251(CHEMBL1922344)
Affinity DataIC50:  28.6nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358264(CHEMBL1922234)
Affinity DataIC50:  31.1nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209920(7-({[1-(5-chloro-2-methoxy-benzenesulfonyl)-piperi...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358276(CHEMBL1922342)
Affinity DataIC50:  41.3nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358275(CHEMBL1922343)
Affinity DataIC50:  41.4nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209915(7-({[1-(3-chloro-benzenesulfonyl)-piperidin-4-yl]-...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358265(CHEMBL1922236)
Affinity DataIC50:  50.3nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataIC50:  54.6nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209896(7-({methanesulfonyl-[1-(2-methoxy-5-methyl-benzene...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358272(CHEMBL1922340)
Affinity DataIC50:  59.8nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041993(CHEMBL3359544)
Affinity DataIC50:  61nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358259(CHEMBL1922229)
Affinity DataIC50:  62.6nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358273(CHEMBL1922339)
Affinity DataIC50:  64.2nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209914(7-({[1-(2,5-dichloro-benzenesulfonyl)-piperidin-4-...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041992(CHEMBL3359543)
Affinity DataIC50:  66nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041995(CHEMBL3359569)
Affinity DataIC50:  68nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50041994(CHEMBL3359545)
Affinity DataIC50:  68nMAssay Description:Inhibition of human factor 10a using S-2222 chromogenic substrate assessed as hydrolysis by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358261(CHEMBL1922230)
Affinity DataIC50:  73.4nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358274(CHEMBL1922341)
Affinity DataIC50:  86.1nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM31459(CHEMBL224485 | substituted biphenyl derivative, 21)
Affinity DataIC50:  89nMAssay Description:Inhibition of human TF/FVIIa complex by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209905(7-{[(methylsulfonyl)(1-pyridin-4-ylpiperidin-4-yl)...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358254(CHEMBL1922233)
Affinity DataIC50:  99.2nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209908(7-({[1-(2,5-dichloro-thiophene-3-sulfonyl)-piperid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358257(CHEMBL1922226)
Affinity DataIC50:  103nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358253(CHEMBL1922240)
Affinity DataIC50:  106nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358262(CHEMBL1922231)
Affinity DataIC50:  118nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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